Dr Chan, Kok Ping - Profile

UserID: 7542
Email: chan_kok_ping@ices.a-star.edu.sg
Organization: Institute of Chemical & Engineering Sciences (ICES), A*STAR
Department : Chemical Synthesis Laboratory @ Biopolis
My Page
Keywords :
affinity tags
anti-cancer drugs
biological probes
natural products

Last Login Date : 28/07/2015 11:29:18
Last Updated Date : 28/07/2015 11:32:07

Summary :
Research Area : Cancer/Oncology
Cell Development (incl. Cell Division and Apoptosis)
Chemistry
Organic Chemistry
Pharmaceutics
Protein Targeting and Signal Transduction
Education :
PhD 2007 Nanyang Technological University Singapore
Bachelor 2000 National University of Singapore Singapore

Employment History

Designation Duration Organization Country
Postdoctoral Fellow 2007-2009 Harvard University United States
Process Chemist 2000-2003 GlaxoSmithKline Singapore

Publications

Author Title Journal Year Vol: Page
Kenneth M. Lum , Vanessa J. Xavier , Michelle J.-H. Ong , Charles W. Johannes and Kok-Ping Chan Stabilized Wittig olefination for bioconjugation CHEM COMMUN 2013 49/11188
Ashootosh Tripathi, Jonathan Puddick, Michele R. Prinsep, Matthias Rottmann, Kok Ping Chan, David Yu-Kai Chen, Lik Tong Tan Lagunamide C, a cytotoxic cyclodepsipeptide from the marine cyanobacterium Lyngbya majuscula Phytochemistry 2011 72 / 2369-2375
Chan, Kok Ping; Chen, David Y.-K. Chemical Synthesis and Biological Evaluation of the Englerin Analogs ChemMedChem 2011 6(3) / 420-423
Myers, Andrew G.; Wulff, Jeremy Earle; Siegrist, Romain; Nising, Carl Friedrich; Chan, Kok Ping Targeting the oncoprotein nucleophosmin PCT Int. Appl. 2009 WO 2009020768 A1 200
Chan, Kok-Ping; Ling, Yvonne Hui; Loh, Teck-Peng. Formal synthesis of (+)-SCH 351448: the Prins cyclization approach. CHEM COMMUN 2007 9 / 939-941
Chan, Kok-Ping; Ling, Yvonne Hui; Chan, Jocelyn Li-Ting; Loh, Teck-Peng. Stannane-Free Chemoselective Hydrodehalogenation of 4-Halotetrahydropyrans: Scope and Application to Natural Product Synthesis. J ORG CHEM 2007 72(6) / 2127-2132
Chan, Kok-Ping; Seow, Ai-Hua; Loh, Teck-Peng. Stereochemical Prins cyclization: electronic versus steric effects on the synthesis of 2,4,6-trisubstituted tetrahydropyran rings. TETRAHEDRON LETT 2006 48(1) / 37-41
Chan, Kok-Ping; Loh, Teck-Peng. Prins Cyclizations in Silyl Additives with Suppression of Epimerization: Versatile Tool in the Synthesis of the Tetrahydropyran Backbone of Natural Products. ORG LETT 2005 7(20) / 4491-4494
Chan, Kok-Ping; Loh, Teck-Peng. Lewis acid-catalyzed one-pot crossed Prins cyclizations using allylchlorosilane as allylating agent. TETRAHEDRON LETT 2004 45(45) / 8387-8390
Lee, C. L.; Chan, K. P.; Lam, Y.; Lee, S. Y. Solid-phase combinatorial synthesis of 1,4-benzoxazin-3(4H)-one and 1,4-benzothiazin-3(4H)-one derivatives. TETRAHEDRON LETT 2001 42(6) / 1167-1169

Patents

Patent Title Patent Number Year Awarded Patent Country
Myers, Andrew G.; Wulff, Jeremy Earle; Siegrist, Romain; Nising, Carl Friedrich; Chan, Kok Ping. Targeting the oncoprotein nucleophosmin. PCT Int. Appl. (2009), 227pp. PIXXD2 WO 2009020768 A1 20090212 2009 United States

Collaborations

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Project Institution/Organization Name Description From Year To Year
Target Identification of Englerin A using Stable I IMCB 2011 2012

Grant

Project Title
Target Identification of Englerin A using Stable Isotope Labelling in Cell Culture (SILAC) Technology